The inaugural 2026–2028 BRITE cohort brings together doctoral students from chemistry, pharmaceutical sciences, and engineering.
2026–2028 cohort
Anastasia Ignashkina
PhD program
Pharmaceutical Sciences
Faculty mentor
Hossam Hammouda
Research
Seeks small-molecule modulators of currently undruggable proteins involved in multiple myeloma bone disease, toward precision anticancer therapeutics. Her work links high-throughput and DNA-encoded library screening, mass spectrometry, and biophysical validation by surface plasmon resonance and microscale thermophoresis with an AI-enabled drug-discovery platform, in which predictions guide experiments and results refine the next round of predictions. Cell-based assays and organoid models connect binding to biological function.
Petros Koster
PhD program
Chemistry
Faculty mentor
Michael Ross
Research
Uses a peptide-library approach to learn how short, intrinsically disordered peptides control the binding of metabolites to nanoparticles, with the goal of predictive design rules for responsive biomaterials. Target analytes include CO2, lactate, disease-relevant cations such as sodium, calcium, and magnesium, and pH. Later stages of the work aim at functional hydrogels, cellular delivery, and medical device applications.
Stephanie Sheehan
PhD program
Pharmaceutical Sciences
Faculty mentor
Soumita Das
Research
Studies how the microbial sensor ELMO1 communicates with endolysosomal pathways to sustain chronic inflammation. Her work combines protein–protein interaction studies, plate-based functional assays in wild-type and ELMO1-knockout macrophages, and patient-derived gut organoid models, with the aim of identifying biomarkers and druggable targets for precision immunomodulation.
Timothy Wallace
PhD program
Electrical and Computer Engineering
Faculty mentor
Hengyong Yu
Research
Develops CT reconstruction and image-restoration methods that combine physics-based modeling and machine learning, including deep-learning restoration of low-dose CT. His long-term goal is reliable reconstruction methods that improve clinical imaging.
BRITE Predoctoral Training Program University of Massachusetts Lowell brite@uml.edu